Corrected Evolution

Computer vision fixes protein catalysis, solubility, and expression

Protigy delivers:

  • 5-10 fold increases in solubility, catalytic turnover, and stability
  • 25-50% mutation hit rates
  • written mechanistic insights, not black-box predictions
  • simple fee-for-service pricing

Bypass endless mutation cycles

Find hits immediately

Try Protigy

Protigy identifies a small set of highly impactful mutations. Our advanced platform delivers reliable results in just seven days, providing you with 20-40 validated mutations designed to function both independently and in combination.

Protigy Delivers

Seamless Integration

Our solution slides right into your current workflow, no extra steps or complicated changes needed.

Rapid Results

We deliver mutations for your testing in seven days guaranteed. Historically, we have found many hits in the first round of testing.

Higher Success Rate

Our targeted approach enables a 10% - 50% hit rate and eliminates wasted mutagenesis experiments.

Exclusive Technology

Our patented algorithm ensures accurate and reliable results, tailored for impactful mutations.

Protigy increases

Activity graph
A single PETase variant containing five mutations completely depolymerized consumer PET products within one to two days. Three of the top 10 mutations helped the final enzyme. The paper below describes the derived highly active PETase variant in detail.Reference Link

How we work with you

Say Hello!
We would love to share more about our technology & explain our deliverables
Exchange Information
Provide protein pdb, sequence, desired changes, and mutation requirements
Get Results
We deliver you mutations for testing within seven days

A proven track record

Global Partners:

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We've collaborated with 25 leading organizations worldwide to deliver impactful solutions.

$1B+ Partners:

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Partnered with four industry-leading companies valued at over a billion dollars.

Published Molecules:

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Pioneering contributions to science with eight published molecules.

Read our case studies

Introductory White Paper
Introductory White Paper

Protigy Increases Expression & Solubility in Unrelated Proteins

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External References
External References

Publications that have successfully used the Protigy algorithm for enzyme mutation

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Introductory Presentation
Introductory Presentation

Computer Vision Increases Protein Expression

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